Paired Kidney Exchange

What is a Paired Kidney Exchange?

A paired kidney exchange occurs when a living kidney donor is not compatible with the recipient, and so exchanges kidneys with another donor/recipient pair.  For example, Gary Smith (Founder of the K.E.C and former  paired kidney exchange donor) was an incompatible match for his brother Layne who needed a kidney.  Two brothers, Devin & Jason Baum in Washington state, found themselves in the same situation because they too were an incompatible match to one another.  However, it was found through blood testing that Gary was a match to Jason, the brother in Washington state who needed a kidney, and Jason's brother Devin, was a match to Layne.  Therefor, thanks to the advancements in transplant procedures, a paired exchange of kidneys was able to take place from one unrelated brother to another. (For more details on this story, click here)


To read an article explaining a paired kidney exchange further, please visit: . Listed below are more resources to learn more about Paired Kidney Exchange procedures and donor/recipient opportunities.



Alliance for Paired Donation (APD)
Phone: 419-866-5505, toll-free: 877-APD-4ALL

Program began: 2006
# of Transplants in 2008: 19
# of Transplants to Date: 32


Eligibility: Anyone who has a willing donor can register with APD, even if registered with another network.

How to register: Contact APD directly by phone, visit their website or contact a transplant center that partners with APD. See list on website.

Additional Services: Financial assistance for transplant travel expenses, post surgery medications and other unforeseen financial struggles related to surgery.

List of Partners:

  • Match runs done monthly
  • Uses altruistic donors to form Non-simultaneous Extended Altruistic Donor Chains (NEAD Chains) which allow donors to "pay it forward” after their loved one receives a transplant - eliminating the need for simultaneous transplants (See details on website)
  • Website features animation of paired donation and NEAD chain processes
  • There are currently 75 Alliance Partners in 27 states but this list is growing

  • California Pacific Medical Center

    Phone: 1-877-427-6289


    # of Transplants: 220 (Living Donor -- 91)

    Eligibility: Anyone is eligible to enroll

    Contact: [email protected]

    Additional Links:

    The Kidney Team runs data for interested donor-recipient pairs on our kidney transplant wait list, using a new software, Silverstone Solution’s Matchmaker©, to identify potentially compatible donor-recipient pair(s) with whom a paired kidney transplant may be feasible. ?Data suggests that an individual has about a 1 in 5 chance of finding a compatible donor-recipient pair.

    Johns Hopkins Kidney Paired Donation Program
    Phone: 410-614-6074, option #1 or 888-908-5728

    Website: - Baltimore, MD

    Program began: 2001

    # of Transplants to Date: 54 (as of 1/08)

  • Match runs are done monthly.
  • Compatible pairs interested in finding a six antigen match are encouraged to enter the registry, which improves the chances of more successful matches being found.
  • Transplants are typically done simultaneously, although in certain situations, this is not the case.
  • This center also offers a Blood Type Incompatible Transplant Program, a Positive Crossmatch and Sensitized Patient Program and an Altruistic Donor Program.
  • shares donor/recipient pairs with a number of regional programs in the U.S. and receives donor/recipient pairs from a number of other transplant centers to include in its database.

  • National Kidney Registry
    Phone: (800) 936-1627


    # of Transplants in 2010: 130
    # of Transplants to Date: 213

    Eligibility: Anyone is eligible.

    How to register: Register with a participating transplant center or contact the National Kidney Registry if your center is not on the list of participating centers.

  • Match runs done on daily basis.
  • Website offers a comprehensive guide on the transplant process, including pertinent information for donors, recipients and transplant centers, step by step recipient guide, and tips for the best outcome.
  • Affiliated with over 50 leading transplant centers.
  • Matched and transplanted over 50% of incompatible pairs in first two years.

    New England Paired Kidney Exchange (NEPKE)
    Phone: (800) 446-6362


    Program began: 2000 with manual system. *Began with computerized matching in 2005.

    # of Transplants in 2008: 9
    # of Transplants to Date: 38

    Eligibility:  Must have a willing but incompatible donor. Even potential recipients outside of New England are eligible to participate in the registry.

    How to Register:  Contact NEPKE through their website or by phone to register, or contact an affiliated transplant center.

  • Match runs done every 30 to 45 days.
  • Donor travels to recipient’s transplant center.
  • Facilitate two and three way matches (closed chains) with all transplants being done simultaneously.
  • Will work with any transplant center that is willing to work with NEPKE – the center doesn’t have to be a NEPKE partner.
  • Potential recipients can be on multiple paired donation registries. NEPKE is affiliated with 19 transplant centers in the New England area.


    The Paired Donation Network (PDN)
    Phone: 859-291-3431, 1-800-532-0642


    Program began: 2004
    # of Transplants in 2008: 14
    # of Transplants to Date: 62

    Pairs Currently in database:  208

    Eligibility: Anyone who has a donor that isn’t a match.

    How to register:  Through a member hospital or by contacting the Paired Donation Network.

    List of Partners:

    Contact for Updates: Teresa Braun, Executive Director

  • Match runs are done every 60 to 90 days.
  • Kidneys may be transported between hospitals that are within a 1-2 hour drive of each other; otherwise donors are required to travel to their matched recipient's hospital.
  • includes over 140 kidney transplant programs in almost every state.
  • New programs enter the PDN weekly.
  • The Renal Network
  • Renal Organizations
  • Transplant Organizations
  • Network Resource Overview
  • Patient Services Overview
  • Dialysis Unit Locator
    Various Articles
    • African-American Attitudes Toward Kidney Transplant: A Comparative Analysis - Bradley Manton,

       MSW, Renal Research Institute: Carolina Dialysis Carrboro, Carrboro, NC; Caroline Jennette Poulton,

       MSW, University of North Carolina Kidney Center, Chapel Hill, NC;

       (Information and pictures of the renal system)

    • Chronic Kidney Disease, Health Conditions Information; (various articles)
    • Recent Developments in Kidney Transplantation
    • Kidney Paired Donation: Fundamentals, Limitations, and Expansions
    • New research report on paired kidney exchanges and chain transplants
    • Cancer after kidney transplantation in the United States, by Kasiske BL; Snyder JJ;
       Gilbertson DT; et al. (Volume 4: issue 6)

    • Diabetes Mellitus after Kidney Transplantation in the United States, by Bertram L. Kasiske,

       Jon J. Snyder, David Gilbertson, Ajthur J. Matas
    • Risk of Stroke in Kidney Disease, Ninomiya T. Toyoda K (ed): Brain, Stroke and Kidney.

       Contrib Nephrol. Basel, Karger, 2013, vol 179, pp 58-66 (DOI: 10.1159/000346724)

    • Nephrology Nursing: A view from the other end of the dialysis needle; written by:
       St. Peter's Dialysis Nurse Alice Luehr, B.A., R.N., C.N.N, published in Dialysis News and Issues,

       a national renal magazine.  Luehr's feature takes a look at dialysis from a nurse's point of view.
    • The Decline in Living Kidney Donation in the United States: Random Variation or Cause for Concern?

       Rodrigue, James R. Schold, Jesse D. Mandelbrot, Didier A
    • World Kidney Day -Things you should know about kidney transplants - Read Health Related Blogs,

       Articles & News on Diseases & Conversation